Gastrointestinal stromal tumour-sclerosing epithelioid a rare variant: A case report

Gastrointestinal stromal tumours are the most common mesenchymal neoplasms of gastrointestinal tract. They should be differentiated from other types tumours. GISTs harbour specific activating mutations in KIT or platelet-derived growth factor receptor a (PDGFRA) tyrosine kinases, which makes them responsive to pharmacologic inhibitors. The advances identification GISTs, by its molecular and immunohistochemical basis, have led better understanding rare tract with predictable behaviour outcome, replacing older terminologies like leiomyoma, schwannoma leiomyosarcoma. This report presents case 64 yr. old male recently operated on for sclerosing epithelioid variant tumour.